In 60 percent of strains, knocking out a gene generates mice that are non-viable; that is, the mouse cannot survive without the knocked out gene. The Monell survey revealed that body weight was altered in over a third of the viable knockout staining; 31 % weighed significantly less than handles , while another 3 % weighed more . Extrapolating from the full total quantity of genes in the mouse genome, therefore that over 6,000 genes could potentially contribute to the body fat of a mouse.Both Ramanathan and Forest provides their distinct knowledge and backgrounds to the expanding scientific groups at the Allen Institute. Sharad Ramanathan, Ph.D. Sharad Ramanathan, Ph.D., is going to from the Harvard College of Applied and Engineering Sciences, where he is a Professor of Molecular and Cellular Biology and the Gordon McKay Professor of Applied Physics. His research is focused on understanding how cells and organisms interpret their environment and process signals in order to make decisions, using a mix of computational, experimental and theoretical tools. His lab at Harvard studies the overall design concepts of circuits in a number of species, including mouse, human being, and the C.