Nevertheless, the human process of addiction is much more technical than dopamine launch in the incentive pathways of the mind or the binding occupancy of the endogenous opiate receptors. Cross-cultural studies such as this one reveal that people also needs to appreciate that the non-public distress experienced by addicted patients, and their regularly challenging illness behaviors, are manifestations of complex psychological processes which may be bound and exist within a sociocultural paradigm culturally. Thus, research such as this reminds the scientific community of the complexity of alcoholism and comorbid circumstances.To explore nicotine addiction, investigators focused on 18 healthy adults who had hardly ever smoked or had only ever smoked a few smokes. But instead of providing them with a regular cigarette, the team offered participants pills containing nicotine equal to one-tenth the level of a normal smoke for a number of weeks, and also an identical-looking dummy tablet. The volunteers did not know if indeed they were acquiring nicotine or the placebo. These were only told these were taking supplements that could contain caffeine, sugars, ginseng, chamomile, theobromine, kava or nicotine. ‘We attempted to develop conditions where people could figure out how to become familiar with the subtle mood-altering ramifications of very low doses of nicotine, with the goal of uncovering the reinforcing ramifications of nicotine,’ Griffiths explained.