The most frequently reported treatment-related adverse events of any grade in the docetaxel group had been neutropenia , exhaustion , nausea , and alopecia . Treatment-related severe adverse events were much less frequent in the nivolumab group than in the docetaxel group .5 percent of patients) treatment-related choose adverse events of any grade were rash , pruritus , erythema , diarrhea , hypothyroidism , increased alanine aminotransferase level , increased aspartate aminotransferase level , infusion-related reaction , and pneumonitis .Furthermore, none of the patients with ADHD had been in BD remission during evaluation compared with 31.2 percent of those without ADHD. In keeping with these findings, patients with ADHD had considerably higher mean severity ratings on the Clinical Global Impression Bipolar scale for combined , depressive , and global symptoms. In addition, patients with ADHD acquired higher prices of substance use disorder than those without , particularly regarding cocaine and poly-drug abuse. The researchers also discovered that individuals with ADHD had considerably poorer family adjustment ratings on the Sheehan Disability Scale than those without, at 5.3 versus 4.0. Perugi and group conclude: ‘Our findings claim that ADHD symptoms in adults may impact clinical presentation, prognosis and span of BD.’ They add: ‘Further potential research is required to confirm our findings and to explore treatment implications for the management of BD.’ Certified from medwireNews with permission from Springer Healthcare Ltd.