Most of the histiocytes had been multinucleated and experienced a central wreath of nuclei with a foamy periphery . There was a history of lymphocytes, eosinophils and plasma cells between the histiocytes.. A reddish papule with a yellowish hue A 35-year-old guy presents with an asymptomatic yellowish-red papule on his shoulder. What is this lesion? A 35-year-old man had an asymptomatic, 5 mm papule on his remaining shoulder which experienced persisted for six months. Close examination showed a circumscribed, elevated red papule with a yellowish hue . No comparable lesions were found on general study of his epidermis.Although significant strides have been made towards understanding the biochemical and molecular mechanisms underlying MDC1A, there remains no effective therapy set up to combat this lethal disease. The extensive research team, led by Girgenrath, hypothesized that the complicated pathology observed in MDC1A could be the result of dysregulation of multiple cellular features and processes, meaning that strategies which simultaneously focus on several of those mechanisms may lead to a reduction of symptoms. Related StoriesRUCDR Infinite Biologics awarded $6 million grant from NINDSAmbry Genetics presents groundbreaking TP53 gene data at ASHG; TP53 linked to breast cancerCWRU awarded two NIH grants to create pathology image informatics platform Very few studies have utilized the energy of combinatorial therapy in the context of muscular dystrophy.